Game: Indianapolis Colts @ San Francisco 49ers (currently at O/U 43)
TREND: San Francisco scores at home, Indianapolis scores on the road
- SF OVER: 4-2 (67%) over the last 6 home games
- IND OVER: 5-1 (83%) over the last 6 road games
The lights are bright on Sunday night and both of these teams need a win to keep their playoff hopes alive. Here’s two coaches who have a plethora of innovative plays in their pocket, and this is the type of game to pull those out during a must-win matchup that neither team can afford to lose if they want to be considered legitimate contenders.
Pick: Over 43 (-110)